At the moment, "only" 893 Pokemon exist. In the games, all of the Pokemon have their own set of stats. These combine Attack, Special Attack, HP, Special Defense, Speed, and Defense.
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Defense is a stat that decides how much damage a Pokemon takes when hit with a physical move. And physical moves themselves are (typically) determined by Attack. Usually, Attacks make physical contact with the Pokemon, and so Defense endures or reflects these moves as much as possible.
10 Deoxys
According to Pokemon LeafGreen, "When it changes form, an aurora appears. It absorbs attacks by altering its cellular structure."
Thanks to the change in cellular structure, Deoxys (in Defense Forme) gets a base Defense stat of 160. While not in terms of Defense particularly, it does have the highest Special Defense among all the Psychic-type Pokemon.
Clearly, Deoxys's design originates from aliens as well as the nucleic acid double helix or a chromosome package. The name itself is literally an abbreviation of deoxyribonucleic acid (DNA).
9 Onix
According to Pokemon Sword, "As it digs through the ground, it absorbs many hard objects. This is what makes its body so solid."
One can only wonder how many hard objects Onix absorbed to bolster its body enough for a base Defense stat of 160. In fact, of all unevolved Pokemon, it has the highest amount. (Additionally, Onix is the heaviest!)
Unsurprisingly, Onix is a rock snake, possibly even inspired by the Mongolian death worm. Its name is merely a corruption of "onyx" (the mineral).
8 Bastiodon
According to Pokemon Ultra Moon, "This Pokémon is from roughly 100 million years ago. Its terrifyingly tough face is harder than steel."
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Whatever material it is made of, Bastiodon and its face get it to a base Defense stat of 168. Put together, Bastiodon has the highest base Defense and Special Defense!
Since it is a Fossil Pokemon, it draws inspiration from a dinosaur but also a fortress. Bastiodon's name is a combination of "bastion" and "don," a suffix used in many dinosaur names.
7 Aggron
According to Pokemon X, "It claims an entire mountain as its own. The more wounds it has, the more it has battled, so don't take it lightly."
It is no wonder Aggron can endure battle after battle, wound after wound because it has a base Defense stat of 180.
Literally, it is a dinosaur, more specifically a Triceratops, but decked out in armor like a knight. Aggron's name is a combination of "aggressive" and "iron."
6 Cloyster
According to Pokemon Sword, "Its shell is extremely hard. It cannot be shattered, even with a bomb. The shell opens only when it is attacking."
That is one tough shell indeed as Cloyster has a base Defense stat of 180. In fact, of all the Water-type Pokemon, it reigns supreme here.
Origin-wise, Cloyster is a bivalve with a black pearl attached. The name itself is just a combination of "clam" and "oyster," which is pretty self-explanatory!"
5 Avalugg
According to Pokemon Omega Ruby, "Its ice-covered body is as hard as steel. Its cumbersome frame crushes anything that stands in its way."
When ice feels as hard as steel, that be an Avalugg, which has a base Defense stat of 184. When it comes to Ice-type Pokemon, this is the highest amount.
It is quite actually only an iceberg. Avalugg's name is just a combination of "avalanche" and lug" (meaning, dragging something that is heavy).
4 Regirock
According to Pokemon Sword, "Every bit of Regirock's body is made of stone. As parts of its body erode, this Pokémon sticks rocks to itself to repair what's been lost."
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While Regirock is made up of mere stones, it has a base Defense stat of 200.
Obviously, Regirock is a golem...a rock golem, that is. Regarding its name, that is a combination of "regis" (Latin for "royal") and...well...rock, of course!
3 Steelix
According to Pokemon X, "Tempered underground under high pressure and heat, its body is harder than any metal."
Yes, no metal out there is tougher than Steelix, which has a base Defense stat of 200. And no Ground-type Pokemon compares, as it boasts the highest amount in that regard.
Steelix is a steel snake, possibly drawing influence from a wyrm (dragon worm). The name itself, in case it was not obvious already, is a combination of "steel" and its pre-evolution Onix. Perhaps the word "helix" counts too here, considering Steelix's body.
2 Stakataka
According to Pokemon Ultra Sun, "It appeared from an Ultra Wormhole. Each one appears to be made up of many life-forms stacked one on top of each other."
Who knows how many life-forms are stacked on top of each other but there are enough for Stakataka to have a base Defense stat of 211. Of all the Rock-type and Steel-type Pokemon, it has the highest amount. (Also, Stakataka is the heaviest Rock-type Pokemon!)
Design-wise, it looks like a castle. And regarding Stakataka's name, it is a combination of "stack" and "attack." (Get it?)
1 Shuckle
According to Pokemon Alpha Sapphire, "Shuckle quietly hides itself under rocks, keeping its body concealed inside its hard shell while eating berries it has stored away. The berries mix with its body fluids to become a juice."
While eating berries, Shuckle is chilling, because thanks to its hard shell it gets a Defense stat of 230. It has not only the highest Defense but Special Defense too of all the Pokemon currently obtainable.
When it comes to origin, Shuckle is an endolith. The name itself, on the other hand, is a combination of "shuck" (meaning a husk or pod) and "turtle."
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