The Metal Gear Solid games have always been a unique mix of equally bizarre storytelling and gameplay mechanics. The series has enjoyed massive critical and commercial acclaim right from its inception on the PlayStation in 1998. The series has evolved a lot over the years, and each entry would bring a bunch of new ways to interact with the game, which meant each game enjoyed long stretches of fan-hype.
2015's Metal Gear Solid 5: The Phantom Pain has proven to be a painful death for the series, following the departure of series creator Hideo Kojima from Konami. Attempts to continue the series, like Metal Gear Survive, seem to have been in vain. Now, rumors seem to imply that Konami is willing to outsource development on the Metal Gear property to new studios. All of this chaos has made the possibility of a Metal Gear Solid 6 seem highly unlikely, which may be disappointing for many fans.
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Metal Gear Solid 5: The Phantom Pain was the last Kojima-led Metal Gear Solid game developed. The game's development history was a rough one, ripe with difficulties both known and unknown. The final stretches of development saw Kojima Productions' role greatly reduced, following a disagreement with the company's higher executives who wished to pour more resources into the mobile market. While the game was great in its own right, the cracks were definitely visible, with reports of cut content and recycled missions in the later acts of the game.
After the release of Metal Gear Solid 5 and Kojima's subsequent departure, Konami tried to capitalize on the franchise's fandom with Metal Gear Survive. This game turned the tactical espionage action of the original games into a generic zombie survival game. Fans were furious to see such a downgrade, and the negative critical and commercial reception supports that sentiment.
Currently, there are no prominent rumors or reports regarding a new mainline entry in the Metal Gear Solid series. It wouldn't be an understatement to say that a lot of what fans love about the games is the sheer creativity and artistry beneath the plethora of ideas that Kojima brings to the table. That being said, it's definitely possible for Konami to create a successor without Kojima at the helm, but fans shouldn't expect anything related for some time now.
It's definitely true that there isn't any Metal Gear Solid 6 in the works at the time of writing, but rumors have been running rampant regarding a remake of the original Metal Gear Solid collection. Konami is reportedly licensing third-party studios to work on the Metal Gear Solid property, backing rumors regarding Metal Gear Solid remakes, which are supposedly exclusive to the PS5 and PC. While it isn't confirmed at the moment, Bluepoint Games is rumored to be working on the remake(s).
Fan-speculation suggests that if such a remake garners a considerable amount of commercial and critical acclaim, it would result in the commencement of future entries in the Metal Gear Solid franchise. However, fans should note that these are just speculation, and all of this should be taken with a grain of salt.
Metal Gear Solid 6 is not currently in development.