Spider-Man has one of the best rogues' galleries in all superhero history, and over the last 60+ years, every villain has gotten their own time in the spotlight. While many long-time Spidey fans will have their own particular favorite comic runs that they think best showcase each villain, there are a handful that are just considered too influential to not read. For the Green Goblin, it's the original Night That Gwen Stacy Died arc. For Venom, it's the Separation Anxiety run. For Doc Ock, it's the Superior Spider-Man comic. And for Kraven the Hunter, it's Kraven's Last Hunt, a story that Marvel's Spider-Man 2 could've easily leaned on.