Behind all the cheesy one-liners and over-the-top monster designs, Resident Evil has always been a series about the dangers of biological experimentation and financial greed, and since so many characters have been caught in the crossfire, it's led to some incredibly sad backstories. Considering just how dangerous the world of Resident Evil is, with B.O.W attacks and viral outbreaks becoming a common occurrence, it's inevitable that a few individuals would have a few sad stories about how they became involved in the series' most prominent events.