In the early 2000s, a hilarious comedy sitcom about a working-class family in America aired. Malcolm in the Middle, starring Frankie Muniz, Bryan Cranston, and Jane Kaczmarek, followed the experiences of the titular character Malcolm, the middle child in a family of four siblings. The series premiered in January 2000 and ran for seven seasons until 2006. The series had an opening title sequence made up of clips from the show itself and other media backed by the song "Boss of Me" by alt-rock group They Might Be Giants.