The overwhelming majority of isekai anime focuses on two main genres; action and fantasy. But as this genre grew and matured, more and more series began to incorporate other genres into their isekai stories. One of the most popular ones has to be isekai+comedy. There have been several great series in this genre mix, such as How Not to Summon a Demon Lord, Reincarnated as a Vending Machine, and Uncle from Another World, just to name a few.