Mandrake is a main magical component in many magical stories and plots, and Hades 2 is no exception. With this rare item, Melinoe can upgrade tools or an Arcana Card, add more Shrines of Hermes to the surface, or gain access to Warding Circles, but this resource is not easy to obtain. Like Cattails, Mandrake does not grow in the open world, so the only way to get it is to grow it yourself.