The Binding of Isaac is one of the most infinitely replayable games ever made. Many people consider this title's immense popularity to be the reason why roguelike games became so popular, allowing for a compelling gameplay loop where players were encouraged to get as strong as possible before finally having the means to take out powerful enemies and bosses who ended their run time and time again. While the roguelike genre has expanded by leaps and bounds following this title, there's no denying that The Binding of Isaac will still hold a special place in the hearts of many gamers who experienced the magic of this title for themselves during its glory days.