One theory claims that the next Fallout game will give its post-apocalyptic golden era treatment to the Bay Area, and that presents a wealth of opportunity for Bethesda. Culturally, historically, geographically, and architecturally, San Francisco is a strong candidate for Fallout 5's setting, and a true-to-life, era-appropriate military experiment undergone in that area seems like just the sort of corporate contracted shenanigans that Vault-Tec would be involved with.