Claire Redfield made her debut in 1998's Resident Evil 2, but she's gone on to become one of Resident Evil's most recognizable and beloved characters to date, having appeared in a myriad of mainline and spin-off games. Unlike other protagonists like Leon and Chris, Claire doesn't start out as some sort of police officer or special agent. Instead, she is simply a civilian looking for her brother who disappeared during the Raccoon City incident.