In the Dragon Ball anime, the villain Fused Zamasu displayed an intriguing transformation known as "mutation" during his climactic battle with Goku, Vegeta, and Future Trunks. This grotesque change granted Zamasu increased size, strength, and durability, allowing him to hold his own against powerful opponents like Super Saiyan Blue Vegito. Despite gaining power, the mutation came at the cost of Zamasu's fragile mental state deteriorating further.