Scream 7 will see the final girl from the previous two entries, Sam Carpenter, make way for the return of the original Scream queen, Sidney Prescott, with Neve Campbell taking the lead once again after Melissa Barrera's firing. Campbell and Barrera appeared together in Scream (2022) in what was supposed to be a passing of the torch, but the horror franchise has now pivoted back to Sidney, but that doesn't mean some of Sam's brutal traits can't be passed on to Sidney in Scream 7.