While there's very little known about the plot for Spider-Man 4, one thing is clear. High school life is over for Peter, Ned, and MJ. Just what's next is very much up in the air and will depend quite a bit on how far the next movie wants to jump into the future. At the end of Spider-Man: No Way Home, the trio were planning their college destinations, though Ned and MJ were heading off to MIT without Peter thanks to the spell that made everyone forget he was the heroic web-slinger, which also made his friends forget he was their friend.