At the heart of HBO's new series Dune: Prophecy is the Bene Gesserit, a powerful sisterhood whose influence is felt in every Dune novel, film, TV show, video game, and more. Dune: Prophecy tells of the Bene Gesserit's early days when they did not yet have the galactic foothold they would come to enjoy by the time of Frank Herbert's original novels. This Bene Gesserit is populated by women who joined up voluntarily, women who have never known life outside the Sisterhood, women with dark secrets, and every walk of life imaginable.